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Wednesday, 29 February 2012

Vitamin B 15 (pangamic acid, calcium pangamate)


Description

Physiologically active water-soluble compound having a vitamin-like properties. No evidence that failure pangamic acid in the body leads to metabolic disorders, therefore, it is not a vitamin, correct to call it a vitamin-like substance.
Breaks in water and exposed to light.

Sources

vegetableanimalssynthesis in the body
Plant seeds (pumpkin, sesame, sunflower), brewer's yeast, whole grain brown rice, whole grains, cantaloupe and watermelon, apricot seeds, walnuts, almonds.Liver and blood.
Pangamic acid is widely distributed in foods.

Action

Serves as a source of free methyl groups.
Improves lipid metabolism, lowers blood cholesterol.
Involved in oxidative processes, increases the absorption of oxygen by tissues, eliminates hypoxia accelerate recovery processes, increases life of cells.
It stimulates the adrenal glands and liver. Protects the liver from cirrhosis.
Stimulates the synthesis of proteins. Increases the content kreatinfosfatav muscle and liver glycogen and muscle (creatine plays an important role in normalizing fenktsionalnoy ability of muscles and optimization energiticheskoe processes in general).
Has anti-antigialuronidaznymi properties and gives ganglioblokiruyuschimi vasodilator effects.
Stimulate the immune response.
Has detoxifying properties, reduces the need for alcohol and prevent hangovers.

Daily maintenance

Accurate daily human need pangamic acid has not been established, but tentatively assumed that the adult she is 1-2 mg per day.

Symptoms of hypovitaminosis

Fatigue.
With a lack of pangamic acid in the body may experience nerve damage, disturbances of glands, lack of oxygen supply of tissues and diseases of the circulatory system (it should be noted that the study was limited).

Statement

Our studies allow us to recommend it pangamic acid for use in the general complex treatment of the following pathologies:
  • various forms of atherosclerosis
  • pneumosclerosis
  • sclerosis, cerebral
  • bronchial asthma
  • pulmonary emphysema
  • chronic hepatitis
  • chronic alcohol intoxication
  • initial stage of liver cirrhosis
  • pruritic dermatosis
  • rheumatism
  • Some diseases of the cardiovascular system (chronic coronary insufficiency)
Vitamin B 15 is assigned to the tolerability of sulfonamides, corticosteroids, and anti-TB drugs.

Dosages

Used calcium salt pangamic acid - calcium pangamat.
The daily dose of vitamin B 15 (pangamat calcium) for oral administration:
AgeDose
Children3 years50 mg
from 3 to 7 years100 mg
from 7 to 14 years150 mg
Adults100-300 mg
The daily dose is recommended to break for 3-4 hours. The treatment course of 20-40 days. Repeated courses may be 2-3 months.

Safety

Contraindications to receive are glaucoma, severe arterial hypertension.
Side effects:
the elderly can cause deterioration, progression adynamia, increased headaches, appearance insomnia, irritability, tachycardia, arrhythmia and cardiac impairment.

Interaction

Pangamic acid effective when taken with vitamins A and E.

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