Vitamin B 15 (pangamic acid, calcium pangamate)

Description

Physiologically active water-soluble compound having a vitamin-like properties. No evidence that failure pangamic acid in the body leads to metabolic disorders, therefore, it is not a vitamin, correct to call it a vitamin-like substance.

Breaks in water and exposed to light.

Sources

vegetable animals synthesis in the body Plant seeds (pumpkin, sesame, sunflower), brewer's yeast, whole grain brown rice, whole grains, cantaloupe and watermelon, apricot seeds, walnuts, almonds. Liver and blood.

Pangamic acid is widely distributed in foods.

Action

Serves as a source of free methyl groups.

Improves lipid metabolism, lowers blood cholesterol.

Involved in oxidative processes, increases the absorption of oxygen by tissues, eliminates hypoxia accelerate recovery processes, increases life of cells.

It stimulates the adrenal glands and liver. Protects the liver from cirrhosis.

Stimulates the synthesis of proteins. Increases the content kreatinfosfatav muscle and liver glycogen and muscle (creatine plays an important role in normalizing fenktsionalnoy ability of muscles and optimization energiticheskoe processes in general).

Has anti-antigialuronidaznymi properties and gives ganglioblokiruyuschimi vasodilator effects.

Stimulate the immune response.

Has detoxifying properties, reduces the need for alcohol and prevent hangovers.

Daily maintenance

Accurate daily human need pangamic acid has not been established, but tentatively assumed that the adult she is 1-2 mg per day.

Symptoms of hypovitaminosis

Fatigue.

With a lack of pangamic acid in the body may experience nerve damage, disturbances of glands, lack of oxygen supply of tissues and diseases of the circulatory system (it should be noted that the study was limited).

Statement

Our studies allow us to recommend it pangamic acid for use in the general complex treatment of the following pathologies:

• various forms of atherosclerosis
• pneumosclerosis
• sclerosis, cerebral
• bronchial asthma
• pulmonary emphysema
• chronic hepatitis
• chronic alcohol intoxication
• initial stage of liver cirrhosis
• pruritic dermatosis
• rheumatism
• Some diseases of the cardiovascular system (chronic coronary insufficiency)

Vitamin B ₁₅ is assigned to the tolerability of sulfonamides, corticosteroids, and anti-TB drugs.

Dosages

Used calcium salt pangamic acid - calcium pangamat.

The daily dose of vitamin B ₁₅ (pangamat calcium) for oral administration:

Age Dose Children 3 years 50 mg from 3 to 7 years 100 mg from 7 to 14 years 150 mg Adults 100-300 mg

The daily dose is recommended to break for 3-4 hours. The treatment course of 20-40 days. Repeated courses may be 2-3 months.

Safety

Contraindications to receive are glaucoma, severe arterial hypertension.

Side effects:
the elderly can cause deterioration, progression adynamia, increased headaches, appearance insomnia, irritability, tachycardia, arrhythmia and cardiac impairment.

Interaction

Pangamic acid effective when taken with vitamins A and E.

Vitamin B 13 (orotic acid, uratsilkarbonovaya acid)

Description

Orotic acid - a white crystalline powder.

Sources

Vegetable Animals Synthesis in the body Yeast Milk (especially the horse), liver, dairy products Is synthesized in the intestine, in lactating women excreted in milk

Action

It stimulates the metabolism of proteins in the body, normalize liver function, regeneration of hepatocytes.

Orotic acid is involved in the synthesis of methionine metabolism of folic acid and pantothenic acid.

Orotic acid improves reproductive health, a positive effect on the fetus during pregnancy.

Statement

As a preparation of orotic acid used potassium orotate, the indications for its reception are:

• liver disease, cirrhosis
• Chronic heart failure
• viral hepatitis
• peptic ulcer and duodenal ulcer
• nephropathy
• infectious disease
• postoperative

Demonstrated the efficacy of orotic acid in children from 6 months to 10 years, suffering from various skin diseases (eczema, atopic dermatitis, psoriasis, ichthyosis).

Dosages

Daily dose of orotic acid is:

• 0.5-1.5 g, sometimes up to 3 g for adults,
• 0,125-0,5 g for children 1-3 years
• 0.25-1 g for children 3-8 years old.

Depending on the severity of the disease daily dose and duration of treatment may be increased, as the drug is not toxic.

Safety

Prolonged use of orotic acid did not cause any side effects or complications.

Interaction

Orotic acid is assigned to improve the tolerability of drugs: antibiotics, sulfonamides, rezohina, delagila, steroid hormones.

Vitamin P (bioflavonoids, including citrus)

Vitamin P (bioflavonoids, including citrus)

Vitamin P - bioflavonoids are plant, a group of biologically active compounds (rutin, catechin, quercetin, citrine, hesperidin, eriodiktiol, cyanidin). Only about 150 known bioflavonoid, with similar biological effect. In 1936, A. Szent-Gyorgyi isolated from the peel of the lemon, the active principle, reduces brittleness, capillary permeability in patients with hemorrhagic diathesis and scorbutic guinea pigs. It is called vitamin P (from "permeability" - permeability).

Sources of Vitamin P

Vitamin P is usually in the same plant foods, which meets and ascorbic acid . Especially a lot of vitamin P found in citrus fruits, black currants, rose hips, sorrel, green tea, salad.Slightly less than its presence in the tomatoes, grapes, cabbage, parsley, plums, apples and berries. Also contained in buckwheat, white envelope under the peel of citrus fruits. This vitamin is not produced by the body and therefore must be included in the daily diet.

The daily requirement of Vitamin P

Daily adult requirement routine - 30 mg, Quercetin - 15 mg, gesperedine - 100 mg.

The use of vitamin E

Vitamin E and free radicals

Vitamin E is an effective antioxidant. Catechins in green tea can reduce the cell structure based actions are guided by their property to capture oxygen free radicals and neutralize them. As a powerful natural antioxidants, bioflavonoids protect our body's cells from the damaging effects of free radicals, preventing aging, immunity disorders, the occurrence of various diseases. Preventing free radical activity, bioflavonoids increase the body's resistance to adverse environmental factors, slow the aging process.

Vitamin E and cardiovascular system

Rutin gesperedin, quercetin in the vitamin P have kapillyaroukreplyayuschim property normalize and support the structure, flexibility, function, and permeability of blood vessels, prevent their sclerotic lesion, promote vasodilation and maintaining normal blood pressure, swelling, improve blood circulation, preventing the development of varicose veins .

Bioflavonoids, together with vitamin C , prevent the destruction of hyaluronic acid, which strengthens the "cement" of the cell vessels together. Because of this structure is preserved capillaries, increasing their strength, reduced permeability of the walls of blood vessels, preventing bruising.

Quercetin protects the cardiovascular system from excess cholesterol.

Vitamin P and immunity

Bioflavonoids enhance the availability of vitamin C and extend its influence. They possess antibacterial activity, due catechins, which are involved in the creation of protection against colds and infections.

Vitamin E and cancer

Quercetin because of its antioxidant activity, inhibits the growth of tumor cells, particularly in breast cancer and cancer of the blood.

Vitamin P and inflammation

Vitamin P gently stimulates the adrenal cortex and, thus, increases the synthesis of glucocorticoids, has a therapeutic and prophylactic effect in many states.

Vitamin P and allergies

Vitamin P (in particular, quercetin, catechin, gesperedin) prevents the development of histamine and serotonin (mediators of allergy), providing anti-edema and mild analgesic effect, making it easier for allergic disorders, including asthma.